Tricyclic Cardiotoxicity Treated With Sodium Bicarbonate

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Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report

Poisoning with tricyclic antidepressants is an important cause of drug-related self-poisoning in the developed world and a very common cause of poisoning and mortality in developing countries. Electrocardiographic manifestations of most tricyclic antidepressant-poisoned patients resolve by the administration of 1-2 mEq/kg of sodium bicarbonate. Some rare cases have been reported who have been r...

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Electrocardiographic criteria for tricyclic antidepressant cardiotoxicity.

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Sodium bicarbonate

Major uses Sodium bicarbonate is a main constituent of baking soda/powder. Baking powder is composed of 30% of sodium bicarbonate, with cornstarch, sodium aluminium sulfate, calcium acid phosphate, and calcium sulfate [1]. Sodium bicarbonate may be an ingredient of folk remedies containing turpentine, castor oil, lemon and sugar. It is also added to mouthwashes and dentifrices to prevent dental...

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ژورنال

عنوان ژورنال: Circulation

سال: 2007

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.106.657247